Eventually, Homer decides to talk to Mindy, and say that due to their attraction, they should completely avoid each other. Homer does his best to avoid Mindy, who is falling in love with Homer, but despite his best efforts, they keep ending up together. Eventually, Bart comes back to school in his normal appearance, explaining he is no longer a nerd, but the bullies still decide to beat him up anyway. He is picked on and beaten up regularly by bullies for the duration of the two weeks. These adjustments give Bart the appearance of, and gradually turn him into, a nerd. He also receives a pair of oversized shoes to help his posture, and a spray in his throat to cure the redness, which temporarily gives him a squeaky voice. Bart also finds out he has a dry scalp that can only be treated by matting his hair down with a medicated salve, therefore parting his hair to both sides.

The optometrist decides he has lazy eye and fits him with special, thick glasses he has to wear for two weeks. Meanwhile, Bart is sent to an eye specialist after it is discovered he has poor vision. Meanwhile, Marge is sick with a bad cold, which makes her very unattractive to Homer. Homer does so, and to his horror, he finds they have exactly the same personality and interests. Barney advises Homer to talk to Mindy because they will most likely have nothing in common. A beautiful woman named Mindy Simmons is brought in and Homer finds he is falling in love with her.

After breaking numerous labor laws in hiring a replacement, such as hiring illegal aliens and ducks, the United States Department of Labor demands that Burns make changes in the power plant's policies, including hiring at least one female worker. The other musicians begin to discuss the idea of holding another benefit to repair Bart's arm.After Homer and his coworkers barely escape from a gas leak at the nuclear power plant, Homer's coworker is fired when he asks Mr. The benefit is a success, and Bart feels empathy for Lisa and decides to use the money to build a home for the animals. Meanwhile, Lisa is informed that her animals will be taken to a pound and killed if she cannot find a suitable home for them. In order to raise money for the operation he needs, Bart organizes a benefit concert. A tiger bites Bart's arm, causing extensive nerve damage that leaves him unable to play. After dinner that night, Lisa goes into the attic and finds Bart and his jazz group with the animals she rescued. Having nowhere to put them, Lisa puts them in the attic. On her way home, many other animals join her, including a horde of circus animals. Lisa decides to go back and adopt the sick puppy, but after seeing how sick many of them are, she decides to adopt them all in order to save their lives. But at night, the sick dog comes in a ghost-like form to tell her that his fate is doomed because she chose the other dog over him. At the animal shelter, Lisa picks the cutest puppy over a very sick dog that would otherwise die. Marge, who does not want Lisa to compete against Bart, decides to let her adopt a puppy in order to make her happy. Lisa then tries to overtake Bart in his passion of skateboarding, which ends in failure.

Bart easily overshadows everyone, including Lisa, and a legendary jazz group asks him to play with them, much to Lisa's anger, especially as she is the more experienced and passionate of the two. Lisa asks Bart to jazz along with her quintet, which he does. Eventually, his drumming drives Homer and Marge mad and Lisa suggests to her parents that she can take Bart to a jazz brunch. They then try to chase him in the same fashion, until they stop in the middle of an open bridge and fall into a nearby garbage barge. He practices non-stop, even while asleep, and, in the style of 'The Hardest Button to Button''s video, he walks through Springfield while drumming and leaving a copy of his drum kit behind him, every time he plays it, and literally runs into The White Stripes on the street, earning Bart an enmity with them. Bart gets a kit and instantly becomes a natural at it, imagining that every drum and cymbal is Homer's face. As a result, he is forced to see a competent psychiatrist (from 'Brake My Wife, Please') who suggests Bart get a drum set in order to harness his anger and the energy he has and find the focus and discipline that he needs. Homer and Marge are faced with the angry churchgoers, who have had enough of Bart's antics. The game, however, goes awry when the ball flies into several people's mouths, causing mayhem. Bart, bored and looking to go home early, plays a game of paddle ball. Amber, Homer's 'Vegas wife' from 'Viva Ned Flanders', dies of a drug overdose, so the Simpson family attends her funeral.

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